Common Name : Giffa Tablets
Chinese Pinyin : JiFaZhiPian
English name : Gefarnate Tablets
Product Name : Hui Strengthen-G
Ingredients : Gatifibrate (Acacia Acetate).
Properties: This product is an orange film-coated tablet, which is white after removal of the coating.
Indications: Gastric and duodenal ulcers.
A long-term controlled therapeutic trial of gefarnate (600 mg daily) in the treatment of chronic gastric ulcer was carried out in 32 patients. Assessment was based on the clinical course and on repeated radiological and endoscopic examinations, which were performed after 3-months' treatment, at the end of the 1-year trial period, and towards the end of a follow-up period of approximately 2 1/2 to 3 1/2 years. In men with gastric ulcer, gefarnate proved to be highly effective, with 10 out of the 11 patients who received this treatment showing persistent healing of the ulcer compared with only 4 out of the 11 who were on dummy treatment. In the very small group of women it was not possible to show any difference between treatments. No adverse reactions to gefarnate occurred. These results suggest that gefarnate is a safe and effective treatment for chronic gastric ulcer.
Specifications : 50mg
Dosage: Usually, adults take 50~100mg (1~2 tablets) once a day, 2~3 times a day.
Adverse reactions: Digestive system: Occasionally dry mouth, nausea, constipation, upper abdominal discomfort, oral inflammation and other symptoms.
Liver: Occasionally, serum aspartate aminotransferase (AIT) and alanine aminotransferase (AST) were slightly elevated.
Skin: Occasionally urticaria-like skin symptoms, such as the immediate termination of medication.
Contraindications: Disabled for allergic to this product.
Precautions: Patients with prostaglandin contraindications such as glaucoma should be used with caution.
Drug Interactions : Drug interactions may occur if used in conjunction with other drugs. Consult your physician or pharmacist for details.
Pharmacokinetics: absorption, distribution and excretion
The oral administration of 50 mg/kg of gemcitide showed that the absorption rate was 60-70%. After 6 hours of oral administration, the blood concentration reached its peak. After 24 hours, the urine excreted 12.4%, exhaled 19.5%, and feces excreted 30-40%.
Storage: Dry at room temperature.
Packing : Aluminum plastic blister board, 40 pieces / box.
Validity: 18 months
Approval number : Registration No. H20090150
Company Name : Japan. Sheng Huang Rong Yang Pharmaceutical Co., Ltd.